WebJul 1, 2024 · Cytochrome P450 (CYP) 3A7 is one of the major xenobiotic metabolizing enzymes in human embryonic, fetal, and newborn liver. CYP3A7 expression has also been observed in a subset of the adult population, including pregnant women, as well as in various cancer patients. The characterization of CYP3A7 is not as extensive as other … WebCYP3A7-CYP3AP1. CYP3A4 (C-17) is also recommended for detection of CYP3A4 and, to a lesser extent, CYP3A5 and CYP3A7 in additional species, including equine and canine. Molecular Weight of CYP3A4: 51 kDa. Positive Controls: human liver extract: sc-363766 or PC-3 cell lysate: sc-2220. DATA SELECT PRODUCT CITATIONS 1. Breuker, C., et al. …
A Novel Polymorphic Cytochrome P450 Formed by Splicing of …
WebCYP3A7-CYP3AP1. Synonyms: CYP3A7-3AP1, CYP3A7.1L. Species: Human CYP3A7-CYP3AP1 (100861540) Summary: This locus represents readthrough transcription … WebTwo CYP3A pseudogenes, CYP3AP1 and CYP3AP2, were recently identified 12. Functional CYP3A4 is found in most adults, with 10- to 40-fold variation in its expression. ... CYP3AP1 and CYP3A7; the ... plottel
CYP3A7-CYP3A51P Gene - GeneCards A0A087WV96 …
Webandrosterone as a substrate. CYP3A7.1L was found to be polymorphic due to a mutation at position 6 of the first splicing site of CYP3AP1 (CYP3A7_39256T3A), which ab-rogates the pseudogene splicing. This polymorphism had pronounced interethnic differences and was in link-age disequilibrium with other functional polymor-phisms described in the ... WebAug 5, 2005 · The cytochrome P450 3A7 (CYP3A7) is the most abundant CYP in human liver during fetal development and first months of postnatal age, playing an important role … WebSep 30, 2024 · A novel polymorphic cytochrome P450 formed by splicing of CYP3A7 and the pseudogene CYP3AP1. J. Biol. Chem. (2005) M. Kitada et al. P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16 alpha-hydroxylase of dehydroepiandrosterone 3-sulfate. J. Biol. Chem. plotted value