WebbThe interaction of simvastatin with the hepatic enzyme CYP3A4, as listed by the FDA, has led to the need to limit the doses of simvastatin used during co-therapy with certain antihypertensive agents as follows.7 Simvastatin is limited to 10 mg daily during co-therapy with diltiazem and verapamil, and to a 20 mg daily Webb26 dec. 2024 · He used to study grapefruit-drug interaction but abandoned it years ago, after “I came to the conclusion that it wasn’t very important,” he told me. Some concern …
5 Foods (Besides Grapefruit) That Cause Medication Interactions
Webb1 nov. 1998 · @article{Lilja1998GrapefruitJI, title={Grapefruit juice—simvastatin interaction: Effect on serum concentrations of simvastatin, simvastatin acid, and … Webb1 aug. 2024 · Simvastatin (Zocor, FloLipid) Lovastatin (Altoprev) Other common statins, including fluvastatin (Lescol XL), pitavastatin (Livalo); pravastatin (Pravachol); … black and gold band christchurch
An Overview of Drug Interactions With Grapefruit Juice
WebbAims: Simvastatin, a substrate for CYP3A4, is extensively metabolized during the first pass. Our aim was to investigate the effect of regular consumption of grapefruit juice on the pharmacokinetics of simvastatin. Methods: In a randomized cross-over study with two phases, 10 healthy volunteers ingested grapefruit juice 200 ml or water (control) for 3 … Webb11 nov. 2024 · Because grapefruit can interact withvastatin, you should avoid drinking or eating it if you are taking lovastatin, atorvastat, or simvastatin. Other medications should … Webb22 feb. 2024 · The list of medications that can interact with grapefruit includes commonly prescribed medications that: Fight infection Reduce cholesterol Treat high blood pressure Treat heart problems Prevent organ rejection Treat anxiety Control seizures Minimize motion sickness Treat erectile dysfunction Replace hormones Reduce cough Control pain dave balow slib inc