WebApr 1, 2024 · Similar to the trials with postmenopausal patients, only approximately one-half of HER2-positive women included in the SOFT/TEXT trials received anti-HER2 targeted … WebDit bericht delen. Suppression of Ovarian Function (SOFT) with either tamoxifen or exemestane compared with tamoxifen alone in treating premenopausal women with …
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WebDec 16, 2024 · Secondary analysis of SOFT and TEXT trials results in development of a risk score to guide decision making in adjuvant endocrine therapy for premenopausal women … WebDec 23, 2024 · Updated analysis of the combined SOFT plus TEXT trials After a median follow-up of 12 – 13 years, the reduction in the risk of recurrence with 5-year of adjuvant exemestane plus OFS (E+OFS) remained sustained compared with tamoxifen plus OFS (T+OFS). The 12-year disease-free survival rate was 80.5% vs 75.9%, ... dickies duck sherpa lined hooded jacket
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WebApr 14, 2024 · After primary treatment with curative intent for soft tissue sarcoma, patients fulfilling the inclusion criteria and giving informed consent are enrolled. In study protocol patients have their regular chest x-ray once in two months plus ultra-low-dose computed tomography imaging is repeated seven times during the first two years of follow-up. WebJan 4, 2024 · In this study, 101 patients with advanced soft-tissue sarcoma were given 400 mg sorafenib twice daily for 28 days. Eleven patients (15%) had a partial response, and 25 patients (33%) exhibited stable disease, with median progression-free survival and overall survival of 3 and 10 months, respectively. WebJan 12, 2024 · SOFT/TEXT SOFT: SUPPRESSION OF OVARIAN FUNCTION TRIAL TEXT: TAMOXIFEN AND EXEMESTANE TRIAL (at NYU) Both Phase III Trials; Exemestane Plus gonadotrophin- releasing hormone (GnRH) Analogue as adjuvant therapy for premenopausal women with hormone receptor positive breast cancer Goserelin (zoladex 3.6 sc monthly), … citizens memorial hospital careers